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MIRCETTE STORAGE
Keep out of the reach of children. Store MIRCETTE at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.

MIRCETTE USES
Mircette is a "biphasic" oral contraceptive pill. This means that the hormones contained in the tablets are delivered in two stages. Mircette contains 20 mcg of ethinyl estradiol, an estrogen, and 150 mcg of desogestrel, a progestin. The last seven tablets start with two days of "inactive" pills, or placebos and 5 days of 10 mcg of ethinyl estradiol. Since Mircette is a very low-dose oral contraceptive, that is it contains reduced amounts of the hormone estrogen, it may help prevent side effects such as nausea and breast tenderness.

This product combines natural or synthetic estrogens and progestins, similar to the natural sex hormones (estrogen and progesterone) produced in a woman's body. Ethinyl estradiol is an estrogen and desogestrel is a progestin. These products can prevent ovulation and pregnancy. In general, a combination of estrogen and progestin works better than a single-ingredient product. Ethinyl estradiol/desogestrel tablets can also help regulate menstrual flow, treat acne or may be used for other hormone related problems in females.

HOW TO TAKE MIRCETTE
Take mircette pills by mouth. Before you start taking these pills decide what is a suitable time of day and always take them at the same time of day and in the order directed. Swallow the pills with a drink of water. Take with food to reduce stomach upset. Do not take more often than directed.

Most products (except Mircette™) contain a 21-day supply of pills containing the active ingredients. Some products contain an additional 7 pills containing iron or inactive ingredients to be taken during the week of menstruation; this reduces the chance of missing the first day of the next cycle. Most products are to be started on the first Sunday after you start your period or on the first day of your period. You may need to ask your health care provider which day you should start your packet.

If you are taking the Mircette™ product, most of the 28 tablets contain active hormones. This product should be started on the first Sunday after you start your period or on the first day of your period.

SIDE EFFECTS OF MIRCETTE
Severe side effects are relatively rare in women who are healthy and do not smoke while they are taking oral contraceptives. On average, more women have problems due to complications from getting pregnant than have problems with oral contraceptives. Many of the minor side effects may go away as your body adjusts to the medicine. However, the potential for severe side effects does exist and you may want to discuss these with your health care provider.

The following symptoms or side effects may be related to blood clots and require immediate medical or emergency help: chest pain; coughing up blood; dizziness or fainting spells; leg, arm or groin pain; severe or sudden headaches; stomach pain (severe); sudden shortness of breath; sudden loss of coordination, especially on one side of the body; swelling of the hands, feet or ankles, or rapid weight gain; vision or speech problems; weakness or numbness in the arms or legs, especially on one side of the body.

MIRCETTE PRECAUTIONS
Visit your health care provider for regular checks on your progress. You should have a complete check-up every 6 to 12 months. If you have any unusual vaginal bleeding contact your prescriber or health care professional for advice. If you miss a period, the possibility of pregnancy must be considered. See your prescriber or health care provider as soon as you can.

Use an additional method of contraception during the first cycle that you take these tablets.

If you stop taking these tablets and want to get pregnant, a return to normal ovulation can take some time. You may not return to normal ovulation and fertility for 3 to 6 months. Discuss your pregnancy plans with your health care provider.

If you are taking oral contraceptives for the treatment of acne, hirsutism (male-like hair growth), endometriosis or other hormone related problems, it may take several months of continued treatment to notice improvement in your symptoms or condition.

Tobacco smoking increases the risk of getting a blood clot or having a stroke while you are taking mircette, especially if you are more than 35 years old. You are strongly advised not to smoke.

You may get a vaginal yeast infection. If you have never had a yeast infection before, see your prescriber or other health care provider to confirm the problem. If you have had yeast infections in the past and are comfortable with self-medicating the problem, get and use a nonprescription medication to treat the yeast infection.

Taking contraceptive pills does not protect you against HIV infection (AIDS) or any other sexually transmitted diseases.

MIRCETTE INTERACTIONS
Antibiotics or medicines for infections, especially rifampin, rifabutin, rifapentine, and griseofulvin; aprepitant, a medicine used for chemotherapy-induced nausea and vomiting; barbiturate medicines for producing sleep or treating seizures (convulsions); bosentan; carbamazepine; caffeine; clofibrate; cyclosporine; dantrolene; grapefruit juice; hydrocortisone; medicines for anxiety or sleeping problems, such as diazepam or temazepam; medicines for mental depression; medicines for diabetes, including troglitazone and pioglitazone; mineral oil; modafinil; mycophenolate; nefazodone; oxcarbazepine; phenytoin; prednisolone; ritonavir or other medicines for the treatment of the HIV virus or AIDS; selegiline; soy isoflavones supplements; St. John's wort; tamoxifen or raloxifene; theophylline; topiramate; warfarin.

MIRCETTE MISSED DOSE
Try not to miss a dose. If you do, it may be necessary to consult your health care professional, especially if you are taking Mircette™.

For all products (except Mircette™)
21-day schedule: If you miss one dose, take it as soon as you remember and then take the next pill at the regular time as usual. You may take 2 tablets in one day. If you miss two doses (days) in a row, take 2 tablets for the next 2 days, then, continue with your regular schedule. Whenever 1 or 2 doses are missed, you should use a second method of contraception for the next 7 days in addition to taking the pills. If you miss three doses in a row, you should notify your physician or other health care professional for instructions. You will probably need to throw away the rest of the tablets in that cycle pack and start over. Another method of contraception should be used until at least 7 doses have been taken in the new cycle. Missing a pill can cause spotting or light bleeding. Make sure that no more than 7 days pass at the end of the 21 day cycle, before you start your next pack of pills.

28-day schedule: Follow the same directions as above for the first 21 days of the schedule. If you miss 1 of the last 7 pills, you can either double the dose or skip it, but it is important to start the next month's cycle on the scheduled day.

For Mircette™: You will need to contact your health care provider for specific instructions based on which tablets have been missed, for how many days they have been missed, and based on what week of your current cycle you are currently taking tablets.

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