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Storage:
Store antabuse at room temperature between 59 and 86 degrees F (between
15 and 30 degrees C) away from moisture and sunlight. Do not store
in the bathroom.
Uses of Antabuse
Antabuse is used to help treat alcoholism. Antabuse is not
a cure for alcoholism and must be used in combination with supportive
therapy and counseling. Antabuse must never be used without
a person's knowledge.
Side Effects of Antabuse
Antabuse may cause headache, drowsiness, restlessness, skin rash,
acne, garlic-like aftertaste, changes in vision. Inform your doctor
if any of these effects persist or worsen. Unlikely to occur but
report immediately: tingling hands or feet, fatigue, weakness, loss
of appetite, nausea, vomiting, strong stomach pains, dark urine,
yellowing of the eyes or skin. If you notice other effects not listed
above, contact your doctor or pharmacist.
How to use Antabuse
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Take Antabuse by mouth, usually one or two tablets daily as directed
by your doctor. Tablets can be crushed or mixed with liquid if swallowing
is a problem. Do not take antabuse for at least 12 hours after drinking
alcohol. While taking antabuse, it is extremely important you avoid
alcohol in all forms including beer, wine, aftershave lotions, mouthwash,
colognes, liquid medications. Read labels carefully, including those
of nonprescription products, and ask your pharmacist about the alcohol
content if you are uncertain.
Antabuse Precautions
Tell your doctor your medical history, especially: heart disease,
liver or kidney disease, psychiatric problems, diabetes, any allergies
(especially to rubber or pesticides). Antabuse causes an intolerance
to alcohol. Drinking alcohol while on anatbuse can cause serious
effects that can last from 30 minutes to several hours. It produces
an unpleasant reaction of flushing, headache, nausea, vomiting,
dizziness, sweating, pounding heart (palpitations), blurred vision
or weakness when even small amounts of alcohol are ingested. These
disulfiram-alcohol reactions can occur up to two weeks after the
medication has been stopped. Because antabuse can cause drowsiness,
use caution when driving or engaging in activities requiring alertness.
Antabuse should be used only when clearly needed during pregnancy.
Discuss the risks and benefits with your doctor. It is not known
if disulfiram is excreted into breast milk. Consult your doctor
before breast-feeding.
Antabuse Drug Interactions
Disulfiram can affect the way your body reacts to other drugs. Tell your doctor
about all the medications you use (both prescription and nonprescription),
especially: amitriptyline, isoniazid, metronidazole, theophylline,
phenytoin, warfarin. Do not start or stop any medicine without doctor
or pharmacist approval.
Antabuse Overdose
If overdose is suspected, contact your local poison control center or emergency
room immediately. Symptoms of overdose may include unsteadiness,
unusual bleeding or bruising, facial flushing, decreased sexual
ability, fainting, memory loss, garlic or rotten egg breath, metallic
taste, and seizures.
Notes:
Do not allow anyone else to take this medication. Laboratory and/or medical tests (e.g., liver function and blood counts) may be performed to monitor
your progress.
Missed Dose:
If you miss a dose of antabuse, take as soon as remembered if it
is within 12 hours of the missed dose. If it is past 12 hours when
you remember, skip the missed dose and resume your usual dosing
schedule. Do not double the dose to catch up.
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